Pharmacological and Toxicological Screening Methods-I (MPL103T) M.Pharma Question Paper

 

MPL-103T

M.Pharmacy (PCI), I Semester

Examination, November 2022

                           Pharmacological and Toxicological Screening Methods-I 

                                                                    Time: Three Hours

                                                                                                                                    Maximum Marks: 70

Note:    i) Attempt any five questions. 

             ii) All questions carry equal marks.

1-                1. a) What are the physical facilities are required for animals as per CPCSEA?

                 b) What are the Factors required for Micro Environment of the Animals?

             2. a)What are the Animal Breeding methods used in laboratory explain?

                 b) Give a note on penetrating capitative bolt pistols.

             3. a) What are the chemical methods used in euthanasia of animals explain any one method?

                 b)What are the types, composition and functions of CPCSEA.

             4. a) Write a note on hole board test

                 b) What are the parameters are covered under the screening of anxiolytics?

             5. a) Classify the nootropic agents with examples and write the passive avoidance method.

                 b) How the hypolipidemie activity screen test performed in rats?

             6. Write a note on:

                a) Kupffer cell culture.

                b) Paracetamol induced liver damage in rats.

             7. Write the general procedure and principle involved in immunoassay.

             8. Write a note on any two:

                a) Noael method.

                b) Mating behavior iest.

                c) Importance of transgenic animals.

                d)  In-vivo Lipschitz test.